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Anti-NXN/NRX Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NXN/NRX rabbit polyclonal |
Gene Name: | Nucleoredoxin |
Synonyms: | NRX, NXN, TRG 4, FLJ12614 |
Immunogen: | Recombinant protein corresponding to Mouse NXN/NRX |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 48 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 300-1: 1000 | skeletal muscle |
IHC | Mouse | 1: 1000-1: 2000 | kidney |
Background
Nucleoredoxin (NRX/NXN), a relatively uncharacterized member of the TRX family protein, has recently been reported to regulate the Wnt/β-catenin pathway, which itself regulates cell fate and early development, in a redox-dependent manner. Northern blot analysis detected several nucleoredoxin splice variants in adult mouse tissues, with highest expression in testis and skin and lowest expression in liver . It has 3 isoforms produced by alternative splicing. This antibody is specific to NXN.
Images
| Western blot analysis of NXN (GB113565) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using NXN (GB113565) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |