| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PCMT1 rabbit polyclonal |
| Gene Name: | Protein-L-isoaspartate(D-aspartate) O-methyltransferase |
| Synonyms: | PIMT, L-isoaspartyl protein carboxyl methyltransferase, Pcmt1, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase |
| Immunogen: | Recombinant protein corresponding to Mouse PCMT1 |
| Isotype: | IgG |
| Purity: | Affinity purification |
| Predicted MW. | 25 kDa |
| Observed MW. | 25 kDa |
| Uniprot ID: | P22061, P23506, P22062 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skin, skeletal muscle, testis |
Background
The PCMT1 catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.
Images
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Western blot analysis of PCMT1 (GB111538) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |