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Anti-PDE6C Rabbit pAb (100 μl)
| Reactivity: | H & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' |
Synonyms: | cGMP phosphodiesterase 6C, PDE6C, PDEA2 |
Immunogen: | Recombinant protein corresponding to Mouse PDE6C |
Uniprot ID: | Q91ZQ1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 99 kDa / 98 kDa |
Product Usage Information
WB | Human | 1: 1000-1: 3000 | A549, MCF7, Hep G2 |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | eyeball |
Background
As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP.
Images
| Western blot analysis of PDE6C (GB114472) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse eyeball using PDE6C (GB114472) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat eyeball using PDE6C (GB114472) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded mouse eyeball using PDE6C (GB114472) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded rat eyeball using PDE6C (GB114472) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |