PE Rabbit anti-Mouse CD304/Neuropilin-1 mAb (100 T)

Brand: Abclonal
Cat. #: A26586
Availability: In Stock

$128.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	PE. Ex:565nm. Em:574nm.
Gene Name:	neuropilin 1
Gene Symbol:	Nrp1
Synonyms:	Nrp; NP-1; Npn1; NPN-1; C530029I03
Gene ID:	18186
UniProt ID:	P97333
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 22-856 of mouse CD304/Neuropilin-1 (NP_032763.2).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/ml
Buffer:	PBS with 0.09% Sodium azide,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-Nrp1 antibody

Background

Enables protein kinase binding activity; transmembrane signaling receptor activity; and vascular endothelial growth factor binding activity. Involved in several processes, including nervous system development; regulation of signal transduction; and vasculature development. Acts upstream of or within several processes, including morphogenesis of a branching epithelium; nervous system development; and toxin transport. Located in several cellular components, including endosome; focal adhesion; and neurofilament. Is integral component of postsynaptic membrane. Is expressed in several structures, including cardiovascular system; jaw; lung; nervous system; and sensory organ. Used to study retinal vein occlusion. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human NRP1 (neuropilin 1).

Images

	Flow cytometry: 1×10^6 CHO cells (negative control,left) and CHO (Transfection,right) cells were surface-stained with PE Rabbit anti-Mouse CD304/Neuropilin-1 mAb (A26586,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Mouse CD304/Neuropilin-1 mAb (A26586,5 μl/Test,right).