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| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | plasminogen activator, urokinase receptor |
| Gene Symbol: | Plaur |
| Synonyms: | Cd87; uPAR; u-PAR |
| Gene ID: | 18793 |
| UniProt ID: | P35456 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-297 of mouse CD87 (NP_035243.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Plaur antibody |
Background
Predicted to enable enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including negative regulation of apoptotic signaling pathway; positive regulation of epidermal growth factor receptor signaling pathway; and positive regulation of release of cytochrome c from mitochondria. Is integral component of plasma membrane. Is expressed in several structures, including decidua; early conceptus; and spleen. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human PLAUR (plasminogen activator, urokinase receptor).
Images
 | Flow cytometry: 1×10^6 RAW 264.7 cells (Low expression,left) and C2C12 cells (right) were surface-stained with PE Rabbit anti-Mouse CD87 mAb (A26599,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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