PE Rabbit anti-Mouse Integrin alpha 1/CD49a mAb (100 T)

PE Rabbit anti-Mouse Integrin alpha 1/CD49a mAb (100 T)

Brand: Abclonal
Cat. #: A26653
Availability: In Stock
$108.00
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Reactivity: Mouse    
Applications: FC    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Monoclonal Antibody    
Conjugation: PE. Ex:565nm. Em:574nm.
Gene Name: integrin alpha 1
Gene Symbol: Itga1
Synonyms: Vla1; CD49A; E130012M19Rik
Gene ID: 109700
UniProt ID: Q3V3R4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of mouse Integrin alpha 1/CD49a (NP_001028400.2).
Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Purification Method: Affinity purification
Concentration: 0.02 mg/ml
Buffer: PBS with 0.09% Sodium azide,0.2% BSA, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-Itga1 antibody




Background

CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.




Images

Itga1 antibodyFlow cytometry: 1×10^6 NIH/3T3 cells (negative control,left) and Neuro-2a cells (right) were surface-stained with PE Rabbit anti-Mouse Integrin alpha 1/CD49a mAb (A26653,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry: 1×10^6 Neuro-2a cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Mouse Integrin alpha 1/CD49a mAb (A26653,5 μl/Test,right).



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