Reactivity: | Human, Mouse, Rat |
Applications: | IHC, ELISA |
Host Species: | Rabbit |
Clonality: | Polyclonal antibody |
Gene Name: | proline, glutamate and leucine rich protein 1 |
Gene Symbol: | PELP1 |
Synonyms: | MNAR; P160; PELP1 |
Gene ID: | 27043 |
UniProt ID: | Q8IZL8 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 884-1130 of human PELP1 (Q8IZL8). |
Dilution: | IHC 1:50-1:200 |
Purification Method: | Affinity purification |
Concentration: | 0.41 mg/ml |
Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-PELP1 antibody |
Background
This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants.
Images
![]() | Immunohistochemistry analysis of paraffin-embedded Rat brain using PELP1 Rabbit pAb (A13414) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
![]() | Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma using PELP1 Rabbit pAb (A13414) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
![]() | Immunohistochemistry analysis of paraffin-embedded Mouse spleen using PELP1 Rabbit pAb (A13414) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
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