Reactivity: | Mouse, Rat |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | protein kinase cAMP-activated catalytic subunit beta |
Gene Symbol: | PRKACB |
Synonyms: | CAFD2; PKACB; PKA C-beta; PKA C-beta (PRKACB) |
Gene ID: | 5567 |
UniProt ID: | P22694 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human PKA C-beta (PRKACB) (NP_002722.1). |
Dilution: | WB 1:500-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 1.09 mg/ml |
Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-PRKACB antibody |
Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Images
![]() | Western blot analysis of various lysates using PKA C-beta (PRKACB) Rabbit pAb (A15709) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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