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Anti-PTPRK Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PTPRK rabbit polyclonal antibody |
Gene Name: | Receptor-type tyrosine-protein phosphatase kappa |
Synonyms: | DKFZp686C2268, DKFZp779N1045, PTPK, PTPRK, R PTP kappa |
Immunogen: | Recombinant protein corresponding to Mouse PTPRK |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Uniprot ID: | P35822 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse | 1: 1000-1: 2000 | kidney |
Background
Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.
Images
| Immunohistochemistry analysis of paraffin embedded human kidney using PTPRK (GB114078) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin embedded mouse kidney using PTPRK (GB114078) at dilution of 1: 1500 |
| Immunofluorescence of paraffin embedded human kidney using PTPRK (GB114078) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded mouse kidney using PTPRK (GB114078) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |