Reactivity: | Mouse |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | PerCP. Ex:482nm. Em:678nm. |
Gene Name: | CD4 antigen |
Gene Symbol: | Cd4 |
Synonyms: | L3T4; Ly-4 |
Gene ID: | 12504 |
UniProt ID: | P06332 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-394 of mouse CD4 (NP_038516.1). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-Cd4 Antibody |
Background
Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).
Images
![]() | Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes were surface-stained with PerCP Rabbit anti-Mouse CD4 mAb (A27322,5 μl/Test,orange line) or PerCP Rabbit IgG isotype control (A24204,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). Cells in the gate were used for analysis. |
![]() | Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes were surface-stained with PerCP Rabbit IgG isotype control (A24204,5 μl/Test,left) or PerCP Rabbit anti-Mouse CD4 mAb (A27322,5 μl/Test,right). |
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