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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing human Beclin 1 (coiled-coil, Myosin-like BCL2 Interacting Protein).
Description:
Pre-made adenovirus for over-expression of human Beclin 1 (coiled-coil, Myosin-like BCL2 Interacting Protein), ready to ship and ready to use format.
Gene Name:
Beclin 1 (coiled-coil, Myosin-like BCL2 Interacting Protein)
ACCN:
BC010276
Gene ID:
8678
GI Number:
16307456
Fusion Tag:
C-terminus V5 tag
Promoter:
CMV
Titer:
1×1010~1×1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Beclin 1 (BECN1) plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
Storage:
-80°C
Documents:
