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| Product Category: | Human lentivirus expressing ACTA2 |
| Description: | Premade lentivirus for over-expression of human ACTA2 and control, ready to use format. |
| Gene Name: | actin alpha 2, smooth muscle |
| Gene Symbol: | ACTA2 |
| Synonyms: | ACTSA; SMDYS |
| ACCN: | NM_001141945.3 |
| Gene ID: | 59 |
| Vector: | PLVX-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The gene ACTA2 encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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