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| Product Category: | Human lentivirus expressing AQP4 |
| Description: | Premade lentivirus for over-expression of human AQP4 and control, ready to use format. |
| Gene Name: | aquaporin 4 |
| Gene Symbol: | AQP4 |
| Synonyms: | MIWC; MLC4; WCH4; hAQP4 |
| ACCN: | NM_001317384.3 |
| Gene ID: | 361 |
| Vector: | PLVX-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Additional isoforms, resulting from the use of alternative in-frame translation initiation codons, have also been described. Recent studies provided evidence for translational readthrough in this gene, and expression of C-terminally extended isoforms via the use of an alternative in-frame translation termination codon.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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