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| Product Category: | Human lentivirus expressing ASCL1 |
| Description: | Premade lentivirus for over-expression of human ASCL1 and control, ready to use format. |
| Gene Name: | achaete-scute family bHLH transcription factor 1 |
| Gene Symbol: | ASCL1 |
| Synonyms: | ASH1; HASH1; MASH1; bHLHa46 |
| Gene ID: | 429 |
| Vector: | PDS279_pL-CMV-GFP-ccdB-puro |
| Promoter: | CMV |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The gene ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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