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| Product Category: | Mouse lentivirus expressing Atf3 |
| Description: | Premade lentivirus for over-expression of mouse Atf3 and control, ready to use format. |
| Gene Name: | activating transcription factor 3 |
| Gene Symbol: | Atf3 |
| Synonyms: | LRG-21 |
| ACCN: | NM_007498.3 |
| Gene ID: | 11910 |
| Vector: | VP001-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of ERK1 and ERK2 cascade; and regulation of transcription by RNA polymerase II. Acts upstream of or within gluconeogenesis; negative regulation of DNA-templated transcription; and skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and long bone. Orthologous to human ATF3 (activating transcription factor 3).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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