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| Product Category: | Human lentivirus expressing BAIAP2 |
| Description: | Premade lentivirus for over-expression of human BAIAP2 and control, ready to use format. |
| Gene Name: | BAR/IMD domain containing adaptor protein 2 |
| Gene Symbol: | BAIAP2 |
| Synonyms: | BAP2; WAML; FLAF3; IRSP53 |
| ACCN: | NM_001144888.2 |
| Gene ID: | 10458 |
| Vector: | pLVX-puro |
| Fusion Tag: | EGFP |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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