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| Product Category: | Human lentivirus expressing BCAT1 |
| Description: | Premade lentivirus for over-expression of human BCAT1 and control, ready to use format. |
| Gene Name: | branched chain amino acid transaminase 1 |
| Gene Symbol: | BCAT1 |
| Synonyms: | BCT1; PP18; BCATC; ECA39; MECA39; PNAS121 |
| ACCN: | NM_005504.7 |
| Gene ID: | 586 |
| Vector: | VP053-CMV-MCS-3×Flag-EF1-fLUC-T2A-NEO |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Neomycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The gene BCAT1 encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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