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| Product Category: | Human lentivirus expressing CD82 |
| Description: | Premade lentivirus for over-expression of human CD82 and control, ready to use format. |
| Gene Name: | CD82 molecule |
| Gene Symbol: | CD82 |
| Synonyms: | R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27 |
| ACCN: | NM_001024844.2, NM_002231.4 |
| Gene ID: | 3732 |
| Vector: | pLKO-CMV-MCS-EF1-ZsGreen-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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