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| Product Category: | Human lentivirus expressing CHRNA5 |
| Description: | Premade lentivirus for over-expression of human CHRNA5 and control, ready to use format. |
| Gene Name: | cholinergic receptor nicotinic alpha 5 subunit |
| Gene Symbol: | CHRNA5 |
| Synonyms: | LNCR2 |
| ACCN: | NM_000745.4, NM_001307945.2, NM_001395171.1, NM_001395172.1, NM_001395173.1, NM_001395174.1, NM_001395175.1 |
| Gene ID: | 1138 |
| Vector: | VP004-CMV-MCS-3×Flag-EF1-fLUC-T2A-PURO |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by the gene CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2)
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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