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| Product Category: | Human lentivirus expressing CTSK |
| Description: | Premade lentivirus for over-expression of human CTSK and control, ready to use format. |
| Gene Name: | cathepsin K |
| Gene Symbol: | CTSK |
| Synonyms: | CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2 |
| ACCN: | NM_000396.4 |
| Gene ID: | 1513 |
| Vector: | pCDH-CMV-MCS-EF1-CopGFP-T2A-Puro |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by the gene CTSK is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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