Your shopping cart is empty!
| Product Category: | Human lentivirus expressing CXCR3 |
| Description: | Premade lentivirus for over-expression of human CXCR3 and control, ready to use format. |
| Gene Name: | C-X-C motif chemokine receptor 3 |
| Gene Symbol: | CXCR3 |
| Synonyms: | GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R |
| ACCN: | NM_001142797.2 |
| Gene ID: | 2833 |
| Vector: | pCDH-CMV-MCS-EF1-copGFP-T2A-Puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
You may also be interested in:
