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| Product Category: | Human lentivirus expressing CXCR4 |
| Description: | Premade lentivirus for over-expression of human CXCR4 and control, ready to use format. |
| Gene Name: | C-X-C motif chemokine receptor 4 |
| Gene Symbol: | CXCR4 |
| Synonyms: | FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; WHIMS1; D2S201E |
| ACCN: | NM_001008540.2, NM_001348056.2, NM_001348059.2, NM_001348060.2, NM_003467.3 |
| Gene ID: | 7852 |
| Vector: | VP037-CMV-MCS-3×Flag-EF1-blast |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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