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| Product Category: | Mouse lentivirus expressing Cers1 |
| Description: | Premade lentivirus for over-expression of mouse Cers1 and control, ready to use format. |
| Gene Name: | ceramide synthase 1 |
| Gene Symbol: | Cers1 |
| Synonyms: | to; Lass1; Uog-1 |
| ACCN: | NM_138647.3 |
| Gene ID: | 93898 |
| Vector: | P002-CMV-MCS-3×Flag-EF1-ZsGreen |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a ceramide synthase enzyme, which catalyzes the synthesis of ceramide, the hydrophobic moiety of sphingolipids. The encoded enzyme synthesizes 18-carbon (C18) ceramide in brain neurons. Mice lacking a functional copy of this gene exhibit impaired cerebellar development, locomotion and motor coordination. This protein is transcribed from a bicistronic mRNA, which also encodes growth differentiation factor 1.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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