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| Product Category: | Mouse lentivirus expressing Ddit4 |
| Description: | Premade lentivirus for over-expression of mouse Ddit4 and control, ready to use format. |
| Gene Name: | DNA-damage-inducible transcript 4 |
| Gene Symbol: | Ddit4 |
| Synonyms: | dig2; REDD1; Rtp801; 5830413E08Rik |
| ACCN: | NM_029083.2 |
| Gene ID: | 74747 |
| Vector: | VP051-CMV-MCS-EF1-ZsGreen-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables 14-3-3 protein binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Acts upstream of or within several processes, including cellular response to dexamethasone stimulus; negative regulation of TOR signaling; and negative regulation of glycolytic process. Located in mitochondrion. Is expressed in several structures, including cerebral cortex subventricular zone; reproductive system; and retina nuclear layer. Orthologous to human DDIT4 (DNA damage inducible transcript 4).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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