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| Product Category: | Rat lentivirus expressing Dnm1l |
| Description: | Premade lentivirus for over-expression of rat Dnm1l and control, ready to use format. |
| Gene Name: | dynamin 1-like |
| Gene Symbol: | Dnm1l |
| Synonyms: | DLP1; Drp1; Dnml1 |
| ACCN: | NM_053655.3 |
| Gene ID: | 114114 |
| Vector: | pLVX-Puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables several functions, including BH2 domain binding activity; identical protein binding activity; and protein serine/threonine kinase binding activity. Involved in several processes, including positive regulation of cellular component organization; response to hypoxia; and synaptic vesicle recycling. Located in several cellular components, including Golgi membrane; clathrin-coated pit; and perinuclear region of cytoplasm. Is active in presynaptic endocytic zone membrane and synaptic vesicle membrane. Biomarker of chronic kidney disease; dental fluorosis; pulmonary fibrosis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in encephalopathy due to defective mitochondrial and peroxisomal fission 1 and optic atrophy 5. Orthologous to human DNM1L (dynamin 1 like).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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