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| Product Category: | Human lentivirus expressing ERBIN |
| Description: | Premade lentivirus for over-expression of human ERBIN and control, ready to use format. |
| Gene Name: | erbb2 interacting protein |
| Gene Symbol: | ERBIN |
| Synonyms: | LAP2; ERBB2IP; HEL-S-78 |
| ACCN: | NM_001253699.2 |
| Gene ID: | 55914 |
| Vector: | VP007-CMV-MCS-3×Flag-EF1-puro |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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