| Product Category: | Rat lentivirus expressing Esr1 | 
| Description: | Premade lentivirus for over-expression of rat Esr1 and control, ready to use format. | 
| Gene Name: | estrogen receptor 1 | 
| Gene Symbol: | Esr1 | 
| Synonyms: | Esr; ER-alpha; RNESTROR | 
| ACCN: | NM_012689.1 | 
| Gene ID: | 24890 | 
| Vector: | pCDH-CMV-MCS-EF1-CopGFP-T2A-Puro | 
| Fusion Tag: | 3×Flag | 
| Promoter: | CMV | 
| Selection Antibiotic: | Puromycin | 
| Titer: | ≥1E+8TU/ml | 
| Buffer: | PBS | 
| Storage: | -80°C | 
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus | 
Background
Enables several functions, including phosphatidylinositol 3-kinase regulatory subunit binding activity; promoter-specific chromatin binding activity; and transcription coactivator binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of signal transduction; and reproductive structure development. Located in several cellular components, including T-tubule; perikaryon; and perinuclear region of cytoplasm. Part of protein-containing complex. Used to study several diseases, including Parkinsonism; infertility; obesity; pleurisy; and prostate disease (multiple). Biomarker of cryptorchidism; osteoporosis; and ovarian cancer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bone disease (multiple); breast cancer (multiple); type 2 diabetes mellitus; and vitiligo. Orthologous to human ESR1 (estrogen receptor 1).
Optional Services
| Name | Catalog # | Turnaround Time | View | 
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote | 
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