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| Product Category: | Human lentivirus expressing FAP |
| Description: | Premade lentivirus for over-expression of human FAP and control, ready to use format. |
| Gene Name: | fibroblast activation protein alpha |
| Gene Symbol: | FAP |
| Synonyms: | FAPA; SIMP; DPPIV; FAPalpha |
| Gene ID: | 2191 |
| Vector: | pLVX-Hygro |
| Promoter: | CMV |
| Selection Antibiotic: | Hygromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by the gene FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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