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| Product Category: | Human lentivirus expressing FENDRR |
| Description: | Premade lentivirus for over-expression of human FENDRR and control, ready to use format. |
| Gene Name: | FOXF1 adjacent non-coding developmental regulatory RNA |
| Gene Symbol: | FENDRR |
| Synonyms: | FOXF1AS1; FOXF1-AS1; lincFOXF1; TCONS_00024240; onco-lncRNA-21 |
| ACCN: | NR_033925.1 |
| Gene ID: | 400550 |
| Vector: | VP003-CMV-MCS-EF1-mcherry-t2a-puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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