| Product Category: | Human lentivirus expressing GADD45A |
| Description: | Premade lentivirus for over-expression of human GADD45A and control, ready to use format. |
| Gene Name: | growth arrest and DNA damage inducible alpha |
| Gene Symbol: | GADD45A |
| Synonyms: | DDIT1; GADD45 |
| Gene ID: | 1647 |
| Vector: | PDS279_pL-CMV-GFP-ccdB-puro |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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