Lentivirus GADD45A (5×200 μl)

Lentivirus GADD45A (5×200 μl)

Cat. #: M2074
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing GADD45A    
Description: Premade lentivirus for over-expression of human GADD45A and control, ready to use format.
Gene Name: growth arrest and DNA damage inducible alpha
Gene Symbol: GADD45A
Synonyms: DDIT1; GADD45
Gene ID: 1647
Vector: PDS279_pL-CMV-GFP-ccdB-puro
Fusion Tag: 3×Flag
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.



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