Lentivirus GPSM2 (5×200 μl)

Lentivirus GPSM2 (5×200 μl)

Cat. #: M2544
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing GPSM2    
Description: Premade lentivirus for over-expression of human GPSM2 and control, ready to use format.
Gene Name: G protein signaling modulator 2
Gene Symbol: GPSM2
Synonyms: LGN; CMCS; PINS; DFNB82
ACCN: NM_013296.5
Gene ID: 29899
Vector: VP051-CMV-MCS-EF1-ZsGreen-T2A-PURO
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.



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