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| Product Category: | Human lentivirus expressing HDAC6 |
| Description: | Premade lentivirus for over-expression of human HDAC6 and control, ready to use format. |
| Gene Name: | Histone deacetylase 6 |
| Gene Symbol: | HDAC6 |
| Synonyms: | HD6; JM21; CPBHM; KDAC6; PPP1R90 |
| ACCN: | NM_001321230.2 |
| Gene ID: | 10013 |
| Vector: | pLVX-Puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by the gene HDAC6 belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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