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| Product Category: | Mouse lentivirus expressing Hk2 |
| Description: | Premade lentivirus for over-expression of mouse Hk2 and control, ready to use format. |
| Gene Name: | hexokinase 2 |
| Gene Symbol: | Hk2 |
| Synonyms: | HKII |
| ACCN: | NM_013820.4 |
| Gene ID: | 15277 |
| Vector: | pLKO-CMV-MCS-3×Flag-EF1-fLUC-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables hexokinase activity. Involved in negative regulation of mitochondrial membrane permeability and negative regulation of reactive oxygen species metabolic process. Acts upstream of or within several processes, including carbohydrate phosphorylation; cellular response to leukemia inhibitory factor; and regulation of D-glucose import. Located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human HK2 (hexokinase 2).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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