Lentivirus IL11RA (5×200 μl)

Lentivirus IL11RA (5×200 μl)

Cat. #: M2149
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing IL11RA    
Description: Premade lentivirus for over-expression of human IL11RA and control, ready to use format.
Gene Name: interleukin 11 receptor subunit alpha
Gene Symbol: IL11RA
Synonyms: CRSDA
ACCN: NM_001142784
Gene ID: 3590
Vector: VP001-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO
Fusion Tag: 3×Flag
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.



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