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| Product Category: | Human lentivirus expressing LOXL2 |
| Description: | Premade lentivirus for over-expression of human LOXL2 and control, ready to use format. |
| Gene Name: | Lysyl oxidase like 2 |
| Gene Symbol: | LOXL2 |
| Synonyms: | LOR; LOR2; WS9-14 |
| ACCN: | NM_002318.3 |
| Gene ID: | 4017 |
| Vector: | VP004-CMV-MCS-3×Flag-EF1-fLUC-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The gene LOXL2 encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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