| Product Category: | Human lentivirus expressing MXD3 |
| Description: | Premade lentivirus for over-expression of human MXD3 and control, ready to use format. |
| Gene Name: | MAX dimerization protein 3 |
| Gene Symbol: | MXD3 |
| Synonyms: | MYX; MAD3; BHLHC13 |
| ACCN: | NM_001142935 |
| Gene ID: | 83463 |
| Vector: | pCDH-CMV-MCS-EF1-copGFP-T2A-Puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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