| Product Category: | Human lentivirus expressing MYCN |
| Description: | Premade lentivirus for over-expression of human MYCN and control, ready to use format. |
| Gene Name: | MYCN proto-oncogene, bHLH transcription factor |
| Gene Symbol: | MYCN |
| Synonyms: | NMYC; ODED; MODED; MPAPA; N-myc; FGLDS1; bHLHe37; MYCNsORF; MYCNsPEP |
| ACCN: | NM_001293228.2 |
| Gene ID: | 4613 |
| Vector: | VP087-SFFV-MCS-3×Flag |
| Fusion Tag: | 3×Flag |
| Promoter: | SFFV |
| Selection Antibiotic: | Neomycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
You may also be interested in: