Lentivirus MYCN (5×200 μl)

Lentivirus MYCN (5×200 μl)

Cat. #: M2195
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing MYCN    
Description: Premade lentivirus for over-expression of human MYCN and control, ready to use format.
Gene Name: MYCN proto-oncogene, bHLH transcription factor
Gene Symbol: MYCN
Synonyms: NMYC; ODED; MODED; MPAPA; N-myc; FGLDS1; bHLHe37; MYCNsORF; MYCNsPEP
ACCN: NM_001293228.2
Gene ID: 4613
Vector: VP087-SFFV-MCS-3×Flag
Fusion Tag: 3×Flag
Promoter: SFFV
Selection Antibiotic: Neomycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.



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