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| Product Category: | Human lentivirus expressing MYD88 |
| Description: | Premade lentivirus for over-expression of human MYD88 and control, ready to use format. |
| Gene Name: | MYD88 innate immune signal transduction adaptor |
| Gene Symbol: | MYD88 |
| Synonyms: | WM1; IMD68; MYD88D |
| Gene ID: | 4615 |
| Vector: | VP077-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-Blasticidin |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Mutation: | L265P |
| Selection Antibiotic: | Blasticidin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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