Lentivirus NCBP2 (5×200 μl)

Lentivirus NCBP2 (5×200 μl)

Cat. #: M2499
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing NCBP2    
Description: Premade lentivirus for over-expression of human NCBP2 and control, ready to use format.
Gene Name: nuclear cap binding protein subunit 2
Gene Symbol: NCBP2
Synonyms: CBC2; NIP1; CBP20; PIG55
ACCN: NM_007362.5
Gene ID: 22916
Vector: VP004-CMV-MCS-3×Flag-EF1-fLUC-T2A-PURO
Fusion Tag: Flag
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.



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