| Product Category: | Human lentivirus expressing NR4A1 |
| Description: | Premade lentivirus for over-expression of human NR4A1 and control, ready to use format. |
| Gene Name: | Nuclear receptor subfamily 4 group A member 1 |
| Gene Symbol: | NR4A1 |
| Synonyms: | HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77 |
| ACCN: | NM_001202233.2 |
| Gene ID: | 3164 |
| Vector: | VP010-CMV-MCS-EF1-NEO |
| Promoter: | CMV |
| Selection Antibiotic: | Neomycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The gene NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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