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| Product Category: | Human lentivirus expressing NTRK2 |
| Description: | Premade lentivirus for over-expression of human NTRK2 and control, ready to use format. |
| Gene Name: | neurotrophic receptor tyrosine kinase 2 |
| Gene Symbol: | NTRK2 |
| Synonyms: | OBHD; TRKB; DEE58; trk-B; EIEE58; GP145-TrkB |
| ACCN: | NM_006180.4 |
| Gene ID: | 4915 |
| Vector: | VB900004-2920mnn(pLV[Exp]-EGFP&T2A&Puro-EF1A-hNTRK2[NM_006180.4]) |
| Promoter: | EF1a |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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