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| Product Category: | Mouse lentivirus expressing P2rx7 |
| Description: | Premade lentivirus for over-expression of mouse P2rx7 and control, ready to use format. |
| Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 7 |
| Gene Symbol: | P2rx7 |
| Synonyms: | P2X7R; P2X(7) |
| ACCN: | NM_011027.4 |
| Gene ID: | 18439 |
| Vector: | PDS279_pL-CMV-GFP-ccdB-puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables several functions, including ATP binding activity; extracellularly ATP-gated monoatomic cation channel activity; and lipopolysaccharide binding activity. Involved in several processes, including bleb assembly; negative regulation of cell volume; and positive regulation of NLRP3 inflammasome complex assembly. Acts upstream of or within several processes, including phospholipid transport; positive regulation of cytokine production; and positive regulation of secretion. Located in several cellular components, including external side of plasma membrane; neuromuscular junction; and neuronal cell body. Is expressed in brain; cerebral cortex ventricular layer; heart; and metanephros. Orthologous to human P2RX7 (purinergic receptor P2X 7).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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