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| Product Category: | Human lentivirus expressing P4HA1 |
| Description: | Premade lentivirus for over-expression of human P4HA1 and control, ready to use format. |
| Gene Name: | prolyl 4-hydroxylase subunit alpha 1 |
| Gene Symbol: | P4HA1 |
| Synonyms: | P4HA |
| ACCN: | NM_000917.4 |
| Gene ID: | 5033 |
| Vector: | VP044-CMV-MCS-EF1-puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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