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| Product Category: | Human lentivirus expressing PIK3R5 |
| Description: | Premade lentivirus for over-expression of human PIK3R5 and control, ready to use format. |
| Gene Name: | phosphoinositide-3-kinase regulatory subunit 5 |
| Gene Symbol: | PIK3R5 |
| Synonyms: | p101; FOAP-2; P101-PI3K; F730038I15Rik |
| ACCN: | NM_001251851.2 |
| Gene ID: | 23533 |
| Vector: | VP003-CMV-MCS-EF1-mcherry-t2a-puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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