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| Product Category: | Human lentivirus expressing PRKD3 |
| Description: | Premade lentivirus for over-expression of human PRKD3 and control, ready to use format. |
| Gene Name: | protein kinase D3 |
| Gene Symbol: | PRKD3 |
| Synonyms: | EPK2; PKD3; PRKCN; PKC-NU; nPKC-NU |
| ACCN: | NM_005813.6 |
| Gene ID: | 23683 |
| Vector: | VP004-pLKO-CMV-MCS-EF1-fLUC-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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