Lentivirus PTK2 (5×200 μl)

Lentivirus PTK2 (5×200 μl)

Cat. #: M2248
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing PTK2    
Description: Premade lentivirus for over-expression of human PTK2 and control, ready to use format.
Gene Name: protein tyrosine kinase 2
Gene Symbol: PTK2
Synonyms: FAK; FADK; FAK1; FRNK; FADK 1; PPP1R71; p125FAK; pp125FAK
ACCN: NM_005607.5
Gene ID: 5747
Vector: VP-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO
Fusion Tag: Flag
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.



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