Your shopping cart is empty!
| Product Category: | Human lentivirus expressing PYCARD |
| Description: | Premade lentivirus for over-expression of human PYCARD and control, ready to use format. |
| Gene Name: | PYD and CARD domain containing |
| Gene Symbol: | PYCARD |
| Synonyms: | ASC; TMS; TMS1; CARD5; TMS-1 |
| ACCN: | NM_013258.5 |
| Gene ID: | 29108 |
| Vector: | VP007-CMV-MCS-EF1-puro |
| Fusion Tag: | =+GFP |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
You may also be interested in:
