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| Product Category: | Mouse lentivirus expressing Pgk1 |
| Description: | Premade lentivirus for over-expression of mouse Pgk1 and control, ready to use format. |
| Gene Name: | phosphoglycerate kinase 1 |
| Gene Symbol: | Pgk1 |
| Synonyms: | Pgk-1 |
| ACCN: | BC108372.1 |
| Gene ID: | 18655 |
| Vector: | pLVX-Puro |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Mutation: | K191Q, K192Q |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Many pseudogenes of this gene are found throughout the mouse genome.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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