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| Product Category: | Human lentivirus expressing RGS1 |
| Description: | Premade lentivirus for over-expression of human RGS1 and control, ready to use format. |
| Gene Name: | regulator of G protein signaling 1 |
| Gene Symbol: | RGS1 |
| Synonyms: | 1R20; BL34; IER1; IR20; HEL-S-87 |
| ACCN: | NM_002922.4 |
| Gene ID: | 5996 |
| Vector: | VP002-CMV-MCS-EF1-ZsGreen |
| Promoter: | CMV |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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