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| Product Category: | Human lentivirus expressing RIPK1 |
| Description: | Premade lentivirus for over-expression of human RIPK1 and control, ready to use format. |
| Gene Name: | receptor interacting serine/threonine kinase 1 |
| Gene Symbol: | RIPK1 |
| Synonyms: | RIP; RIP1; AIEFL; IMD57; RIP-1 |
| ACCN: | NM_001354931.2 |
| Gene ID: | 8737 |
| Vector: | VP003-CMV-MCS-3×Flag -EF1-mcherry-t2a-puro |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Mutation: | Y380A |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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